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News | OCD

OCD linkage study published in Biological Psychiatry

A study published in the journal Biological Psychiatry by our group this month implicates chromosome 1p36 in childhood-onset OCD.  The study used linkage analyses in 33 families with OCD from the US.  Several chromosomal regions were implicated, and the 1p36 finding (lod score of 3.77) is the strongest published to date for OCD.  Several brain expressed genes lie in this region, which has also been implicated in childhood major depressive disorder, eating disorders, and a specific deletion syndrome.