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PGENeS’ hoarding study in the news

PGENeS lab members Carol Mathews and Monika Eckfield are quoted in the recent article on hoarding entitled “The Surprising Science Behind Hoarding” in the magazine Pacific Standard.  The lab’s research on how individuals with hoarding process information, and Dr. Eckfield’s graduate work on subtypes of hoarding symptoms are discussed.

 

Pacific Standard article

Lab members in the news:

PGENeS PI Carol Mathews was interviewed by Amy Standen of KQED as a part of a segment on nail biting and related pathological grooming behaviors.  Pathological grooming behaviors, which also include hair pulling (trichotillomania) and skin picking (dermatotillomania) are related to both OCD and TS, and often run in families. Slightly different version of story aired on  KQED Quest on September 17, 2012, and on NPR’s Morning Edition on October 1, 2012.

Genome-wide association studies of TS and OCD published!

The first genome-wide association studies (GWAS) of Tourette Syndrome and obsessive-compulsive disorder (OCD) were published this week in the advance online publications of the journal Molecular Psychiatry.  These studies, which were conducted in parallel, examined the genomes of  thousands of individuals with OCD or TS compared to controls.  Although no statistically significant variants were identified, the studies did identify several potential candidate genes for these related disorders, including some that have been implicated for OCD or TS in previous studies.

Links to the papers are below:

GWAS of TS

GWAS of OCD

OCD linkage study published in Biological Psychiatry

A study published in the journal Biological Psychiatry by our group this month implicates chromosome 1p36 in childhood-onset OCD.  The study used linkage analyses in 33 families with OCD from the US.  Several chromosomal regions were implicated, and the 1p36 finding (lod score of 3.77) is the strongest published to date for OCD.  Several brain expressed genes lie in this region, which has also been implicated in childhood major depressive disorder, eating disorders, and a specific deletion syndrome.

Now recruiting participants!

Recruitment of participants is ongoing for our studies of neurocognition in OCD and compulsive hoarding.  Both individuals with non-hoarding type OCD (and their family members) and healthy controls without OCD or hoarding symptoms are needed.  Please contact us using the link at the above right  for more information and to participate.